Medical Monitoring Manager – Oncology

About the role

Translational Research in Oncology (TRIO) is seeking an experienced physician leader to head its Medical Monitoring Unit. The role ensures the medical and scientific integrity of oncology clinical trials across Phase I‑III, balancing scientific rigor with operational practicality.

Key responsibilities

• Lead, manage and develop the Medical Monitoring Unit, overseeing multiple Medical Monitors.
• Ensure consistent, high‑quality medical monitoring across oncology trials from Phase I through Phase III.
• Provide expert medical guidance on protocol interpretation, safety events, eligibility, and benefit‑risk assessment.
• Act as senior medical point of contact for sponsors, investigators and internal stakeholders.
• Drive consistency, quality standards and best practices across studies and the team.
• Manage resource allocation and priorities across a complex, evolving study portfolio.
• Contribute to study and portfolio‑level planning, aligning with budgets and cross‑functional collaboration.
• Support hiring, coaching and retention of high‑performing medical staff.
• Partner closely with Clinical Operations, Drug Safety, Medical Writing and Regulatory teams.

Required profile

• Medical Doctor (MD) – oncology specialization strongly preferred.
• 8‑10+ years of experience in clinical research, with proven experience as a Medical Monitor in oncology trials (Phase I‑III).
• Strong background in safety review and medical decision‑making in active oncology studies.
• Demonstrated people‑management and team‑leadership experience.
• Experience managing multiple studies or programs simultaneously.
• Fluent English; Spanish is a plus.
• CRO experience strongly preferred; pharma experience also considered.

Required skills

• Medical monitoring of oncology clinical trials.
• Safety review and benefit‑risk assessment.
• Regulatory frameworks (ICH‑GCP, FDA, EMA).
• Clinical trial design and execution.

What we offer

• Opportunity to lead a critical function within an oncology‑focused organization.
• High‑impact role with visibility across senior leadership.
• Exposure to a diverse and scientifically meaningful oncology portfolio.