Postdoctoral Fellow – Human Neuroimmunology & Brain Organoids

About the role

The Laboratory of Professor Jan D. Lünemann at the Djavad Mowafaghian Centre for Brain Health seeks a highly motivated Postdoctoral Fellow to develop human experimental models for studying autoimmune and inflammatory diseases of the central nervous system.

Key responsibilities

• Design and generate human induced pluripotent stem cell (hiPSC)‑derived brain organoids.
• Apply genome‑engineering tools (e.g., CRISPR) to create disease‑relevant models.
• Perform advanced imaging, spectral flow cytometry, and high‑throughput multi‑omics assays.
• Analyze single‑cell and spatial genomics, proteomics, and other omics data using computational pipelines.
• Collaborate with interdisciplinary teams in neuroimmunology, stem‑cell biology, biomedical engineering, and AI‑driven precision medicine.

Required profile

• PhD in neuroscience, immunology, stem‑cell biology, or a related field.
• Strong track record of independent research and scientific curiosity.
• Experience working in multidisciplinary, collaborative environments.

Required skills

• Human induced pluripotent stem cell (hiPSC) technology.
• Brain organoid culture.
• Genome engineering (CRISPR/Cas9).
• Advanced microscopy and imaging.
• Spectral flow cytometry.
• Single‑cell RNA‑sequencing and spatial genomics.
• Proteomics workflows.
• Bioinformatics and computational data analysis.

What we offer

• Fixed‑term 2‑year appointment (possible extension).
• Salary range CAD 65,000–75,000 per year plus benefits.
• Access to world‑class stem‑cell, organoid, imaging, and omics facilities.
• Mentorship from leading experts and a vibrant international research network.