Postdoctoral Research Fellow – Endometriosis Oncogenomics

About the role

The Endometriosis Oncogenomics and Pathology (EDGE) Research Lab at the University of British Columbia seeks a highly motivated Postdoctoral Research Fellow to investigate the malignant transformation of endometriosis into ovarian carcinomas. The role involves multidisciplinary collaboration across molecular biology, genomics, epigenomics, microbiome science, proteomics, and clinical research.

Key responsibilities

• Manage and coordinate incoming specimens, maintaining ethics approvals and hospital relationships.
• Support assay development and validation, focusing on cellular and genotoxic stress assays (IHC/IF).
• Lead review, laser capture enrichment, and whole-genome sequencing of tissue samples, including external sequencing contracts.
• Design studies, interpret data, ensure quality control, and troubleshoot experiments.
• Conduct genomic analysis and integrate multi-omics data, including microbiome and cell-stress phenotypes.
• Collaborate with spatial transcriptomics and functional genomics teams, optimizing laboratory and analytical workflows.
• Contribute to grant applications, manuscripts, reports, and presentations with strong scientific writing.
• Supervise, train, and recruit junior trainees such as undergraduate and graduate students.

Required profile

• PhD in a relevant field (e.g., molecular biology, genetics, cancer biology).
• Experience with low-input whole-genome sequencing and genotoxic stress marker assays.
• Proficiency in immunohistochemistry (IHC) and immunofluorescence (IF) techniques.
• Familiarity with laser capture microdissection and bioinformatics pipelines for multi-omics integration.
• Ability to work within a multidisciplinary team and communicate scientific findings effectively.

Required skills

• Molecular biology
• Genomics
• Epigenomics
• Microbiome analysis
• Proteomics
• Whole-genome sequencing
• IHC/IF assays
• Laser capture microdissection
• Bioinformatics
• Multi-omics data integration
• Spatial transcriptomics

What we offer

• Competitive salary range $65,000‑$75,000 CAD per year.
• Opportunity to lead cutting-edge research on ovarian cancer transformation.
• Collaboration with clinicians, scientists, and external partners.
• Access to state-of-the-art facilities at the Vancouver Hospital Campus.