Senior Statistician II

About the role

AstraZeneca is hiring a Senior Statistician II in Toronto. The role suits someone with enough experience as a statistician in the pharmaceutical industry to work independently on design, delivery and interpretation of preclinical studies, regulatory submissions and/or commercialisation, and to guide less experienced staff. The Senior Statistician II may work directly on projects or support statistical methodological advances.

Key responsibilities

• Provide statistical expertise for complex design and interpretation of preclinical or clinical programmes, internal governance committees, regulatory submissions and/or commercialisation.
• Analyse internal and external information, perform modelling and simulation to inform design decisions and decision criteria.
• Develop statistical analysis plans for complex studies and project deliveries.
• Coach less experienced statisticians on analysis, supporting graphics and analysis tables for study reports, Global Medical Affairs studies or publications.
• Analyse, interpret, summarise and communicate results of complex studies.
• Contribute to regulatory submissions, including overview documents and responses to regulatory questions.
• Identify opportunities to use modelling and simulation, improve methodology and contribute to best practice.
• Under the guidance of a more experienced statistician, produce pragmatic solutions quickly, draft analysis plans, consult with fellow statisticians, medical scientists and other roles, and investigate novel statistical approaches.
• Communicate research and results internally and externally through conferences and journal publications.

Required profile

• MSc or PhD in Statistics, Mathematics (with a substantial statistical component) or recognised equivalent.
• Experience designing, analysing and reporting preclinical or clinical studies in more than one setting.
• Knowledge of key technical and regulatory requirements.
• Communication and collaboration skills.
• Desirable: ability to apply statistical expertise to problems with a quality focus.

Required skills

• Competent statistical programmer in SAS and R.
• Knowledge of statistical methods and applications in study design, analysis and interpretation.

What we offer

• Annual base salary ranging from 109,148.80 to 143,257.80.
• Variable pay bonus and eligibility for an equity-based long-term incentive program.
• Flex benefits and retirement savings program, 4 weeks' paid vacation and personal days.
• Fixed-term and temporary positions have a separate contract benefits program.